A closed-tube methylation-sensitive high resolution melting assay (MS-HRMA) for the semi-quantitative determination of <it>CST6</it> promoter methylation in clinical samples

A closed-tube methylation-sensitive high resolution melting assay (MS-HRMA) for the semi-quantitative determination of <it>CST6</it> promoter methylation in clinical samples

<p>Abstract</p> <p>Background</p> <p><it>CST6</it> promoter is highly methylated in cancer, and its detection can provide important prognostic information in breast cancer patients. The aim of our study was to develop a Methylation-Sensitive High Resolution...

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Bibliographic Details
Main Authors: Dimitrakopoulos Lampros, Vorkas Panagiotis A, Georgoulias Vasilis, Lianidou Evi S
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Cancer
Subjects:
Methylation-sensitive high-resolution melting analysis
Cystatin M
CST6
DNA methylation
Breast cancer
Methylation specific PCR
Online Access:http://www.biomedcentral.com/1471-2407/12/486

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http://www.biomedcentral.com/1471-2407/12/486

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