Specific Colon Cancer Cell Cytotoxicity Induced by Bacteriophage E Gene Expression under Transcriptional Control of Carcinoembryonic Antigen Promoter

Specific Colon Cancer Cell Cytotoxicity Induced by Bacteriophage E Gene Expression under Transcriptional Control of Carcinoembryonic Antigen Promoter

Colorectal cancer is one of the most prevalent cancers in the world. Patients in advanced stages often develop metastases that require chemotherapy and usually show a poor response, have a low survival rate and develop considerable toxicity with adverse symptoms. Gene therapy may act as an adjuvan...

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Bibliographic Details
Main Authors: Ana R. Rama, Rosa Hernandez, Gloria Perazzoli, Miguel Burgos, Consolación Melguizo, Celia Vélez, Jose Prados
Format: Article
Language:English
Published: MDPI AG 2015-06-01
Series:International Journal of Molecular Sciences
Subjects:
carcinoma embryonic antigen
colorectal cancer
E gene
suicide gene therapy
promoter tissue specific
Online Access:http://www.mdpi.com/1422-0067/16/6/12601

Internet

http://www.mdpi.com/1422-0067/16/6/12601

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