S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in Arabidopsis

S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in Arabidopsis

S-acylation is a reversible protein post-translational modification that often regulates protein function at the plasma membrane. Here the authors show that an Arabidopsis extracellular ATP receptor P2K1 mediates phosphorylation of two S-acyltransferases which in turn mediate S-acylation of P2K1 and...

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Main Authors: Dongqin Chen, Fengsheng Hao, Huiqi Mu, Nagib Ahsan, Jay J. Thelen, Gary Stacey
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22854-1
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spelling doaj-5c194a984968487196e81cec81f248662021-05-16T11:09:37ZengNature Publishing GroupNature Communications2041-17232021-05-0112111110.1038/s41467-021-22854-1S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in ArabidopsisDongqin Chen0Fengsheng Hao1Huiqi Mu2Nagib Ahsan3Jay J. Thelen4Gary Stacey5State Key Laboratory of Agrobiotechnology, College of Plant Protection, China Agricultural UniversityState Key Laboratory of Agrobiotechnology, College of Plant Protection, China Agricultural UniversityState Key Laboratory of Agrobiotechnology, College of Plant Protection, China Agricultural UniversityDivision of Biochemistry, C.S. Bond Life Science Center, University of MissouriDivision of Biochemistry, C.S. Bond Life Science Center, University of MissouriDivision of Biochemistry, C.S. Bond Life Science Center, University of MissouriS-acylation is a reversible protein post-translational modification that often regulates protein function at the plasma membrane. Here the authors show that an Arabidopsis extracellular ATP receptor P2K1 mediates phosphorylation of two S-acyltransferases which in turn mediate S-acylation of P2K1 and dampen ATP responses.https://doi.org/10.1038/s41467-021-22854-1
collection DOAJ
language English
format Article
sources DOAJ
author Dongqin Chen
Fengsheng Hao
Huiqi Mu
Nagib Ahsan
Jay J. Thelen
Gary Stacey
spellingShingle Dongqin Chen
Fengsheng Hao
Huiqi Mu
Nagib Ahsan
Jay J. Thelen
Gary Stacey
S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in Arabidopsis
Nature Communications
author_facet Dongqin Chen
Fengsheng Hao
Huiqi Mu
Nagib Ahsan
Jay J. Thelen
Gary Stacey
author_sort Dongqin Chen
title S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in Arabidopsis
title_short S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in Arabidopsis
title_full S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in Arabidopsis
title_fullStr S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in Arabidopsis
title_full_unstemmed S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in Arabidopsis
title_sort s-acylation of p2k1 mediates extracellular atp-induced immune signaling in arabidopsis
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2021-05-01
description S-acylation is a reversible protein post-translational modification that often regulates protein function at the plasma membrane. Here the authors show that an Arabidopsis extracellular ATP receptor P2K1 mediates phosphorylation of two S-acyltransferases which in turn mediate S-acylation of P2K1 and dampen ATP responses.
url https://doi.org/10.1038/s41467-021-22854-1
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AT huiqimu sacylationofp2k1mediatesextracellularatpinducedimmunesignalinginarabidopsis
AT nagibahsan sacylationofp2k1mediatesextracellularatpinducedimmunesignalinginarabidopsis
AT jayjthelen sacylationofp2k1mediatesextracellularatpinducedimmunesignalinginarabidopsis
AT garystacey sacylationofp2k1mediatesextracellularatpinducedimmunesignalinginarabidopsis
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