Behavioral and steroidogenic pharmacology of phenyl ring substituted etomidate analogs in rats

Behavioral and steroidogenic pharmacology of phenyl ring substituted etomidate analogs in rats

Abstract Background Cushing’s syndrome is an endocrine disorder characterized by the overproduction of adrenocortical steroids. Steroidogenesis enzyme inhibitors are the mainstays of pharmacological treatment. Unfortunately, they produce significant side effects. Among the most potent inhibitors is...

Full description

Bibliographic Details
Main Authors: Megan McGrath, Alissa Hofmann, Douglas E. Raines
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Pharmacology and Toxicology
Subjects:
Anesthetic
Corticosterone
Cushing’s syndrome
Etomidate
Hypercortisolemia
Steroidogenesis
Online Access:http://link.springer.com/article/10.1186/s40360-019-0328-4

Internet

http://link.springer.com/article/10.1186/s40360-019-0328-4

Similar Items