Addition of Sildenafil in Patients with Pulmonary Arterial Hypertension with Inadequate Response to Bosentan Monotherapy

Addition of Sildenafil in Patients with Pulmonary Arterial Hypertension with Inadequate Response to Bosentan Monotherapy

BACKGROUND: Pulmonary arterial hypertension (PAH) remains a progressive disease despite improvement when using one of three medication classes: prostanoids, endothelin receptor antagonists or phosphodiesterase-5 inhibitors. Combination therapy has been proposed for patients with unsatisfactory respo...

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Bibliographic Details
Main Authors: Nancy R Porhownik, Hassan Al-Sharif, Zoheir Bshouty
Format: Article
Language:English
Published: Hindawi Limited 2008-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2008/897102

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