Primary immunodeficiency in adults: total variable immune deficiency clinical manifestations, immunological and genetic defects, treatment

Primary immunodeficiency in adults: total variable immune deficiency clinical manifestations, immunological and genetic defects, treatment

The most prevalent form of primary immunodeficiency with a total defect of antibody production in adults is common variable immunodeficiency (CVID). Compared to other forms of primary immunodeficiency, CVID is characterized by later onset of clinical manifestations represented by infectious, autoimm...

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Bibliographic Details
Main Authors: Aleksandr Viktorovich Karaulov, Irina Valentinovna Sidorenko, Vladimir Vladimirovich Androsov, Anna Sergeevna Kapustina, A V Karaulov, I V Sidorenko, V V Androsov, A S Kapustina
Format: Article
Language:Russian
Published: "Consilium Medicum" Publishing house 2011-10-01
Series:Терапевтический архив
Subjects:
primary immunodeficiency
common variable immunodeficiency
intravenous immunoglobulins
Online Access:https://ter-arkhiv.ru/0040-3660/article/view/30936
Description
Summary:The most prevalent form of primary immunodeficiency with a total defect of antibody production in adults is common variable immunodeficiency (CVID). Compared to other forms of primary immunodeficiency, CVID is characterized by later onset of clinical manifestations represented by infectious, autoimmune and malignant diseases. To avoid development of complications and patient incapacitating, it is necessary to make an early diagnosis and initiate regular replacement therapy with intravenous immunoglobulins.
ISSN:0040-3660
2309-5342

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