Experimental Studies of the Effect of Cyclic Mitoguazone Analogues on Antineoplastic Activity of Methotrexate
In the presented study we tested the effect of the bi- and monocyclic analogues of mitoguazone on neoplastic activity of methotrexate in the model of L1210 leukemia in mice. We have demonstrated that combined therapy involving administration of methotrexate with 2-oxo-propanal bis (4,5,6,7 -tetrahyd...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
1998-11-01
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| Series: | Pteridines |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/pteridines.1998.9.4.217 |