C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205

C-Reactive Protein Levels in Systemic Lupus Erythematosus Are Modulated by the Interferon Gene Signature and CRP Gene Polymorphism rs1205

ObjectivesPatients with systemic lupus erythematosus (SLE) often display modest elevations of C-reactive protein (CRP) despite raised disease activity and increased interleukin (IL-) 6. We asked to what extent IL-6 levels, the CRP polymorphism rs1205, and the type I interferon (IFN) gene signature a...

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Bibliographic Details
Main Authors: Helena Enocsson, Birgitta Gullstrand, Maija-Leena Eloranta, Jonas Wetterö, Dag Leonard, Lars Rönnblom, Anders A. Bengtsson, Christopher Sjöwall
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
C-reactive protein
type I interferons
systemic lupus erythematosus
inflammation
biomarker
pentraxins
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.622326/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.622326/full

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