Incidence and epidemiological features of synchronous and metachronous colorectal cancer

Introduction: patients with sporadic colorectal cancer or cases associated with syndromes are at risk of having synchronous or metachronous cancer. Although it is an important subject, Brazilian data on the subject are scarce. Objective: to evaluate the incidence and epidemiological features in pati...

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Main Authors: Eduardo Brambilla, Augusto Cardoso Sgarioni, Guilherme Finger, Guilherme Sartori, Maicon Joel Cimarosti
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2013-04-01
Series:Journal of Coloproctology
Online Access:http://www.sciencedirect.com/science/article/pii/S223793631300021X
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spelling doaj-5bf9696b8972455bae55d848db82f45f2021-07-02T07:02:15ZengThieme Revinter Publicações Ltda.Journal of Coloproctology2237-93632013-04-013325861Incidence and epidemiological features of synchronous and metachronous colorectal cancerEduardo Brambilla0Augusto Cardoso Sgarioni1Guilherme Finger2Guilherme Sartori3Maicon Joel Cimarosti4Universidade de Caxias do Sul, Caxias do Sul, RS, Brazil; Corresponding author.Department of General Surgery, Hospital Geral de Caxias do Sul, Caxias do Sul, RS, BrazilUniversidade de Caxias do Sul, Caxias do Sul, RS, BrazilUniversidade de Caxias do Sul, Caxias do Sul, RS, BrazilUniversidade de Caxias do Sul, Caxias do Sul, RS, BrazilIntroduction: patients with sporadic colorectal cancer or cases associated with syndromes are at risk of having synchronous or metachronous cancer. Although it is an important subject, Brazilian data on the subject are scarce. Objective: to evaluate the incidence and epidemiological features in patients with synchro- nous and metachronous colorectal cancer in a reference service of proctology in the Rio Grande do Sul. Methods: cross-sectional observational study, performed between January and July 2012, analyzing all patients admitted in the service that met the inclusion criteria. A retrospective review of records was performed, noting demographic variables, comorbidi- ties and tumor-related variables. Results: 150 records were analyzed, of which 53.3% were males and mean age was 63 (± 13.01) years old. The most frequently found tumor location was the sigmoid colon and high rectum (50.67%), followed by the lower rectum (36%). Adenocarcinomas were the most prevalent histological subtype (88%), followed by epidermoid tumors (1.33%). Hereditary syndromes were identified in five patients (3.33%), with four being Familial adenomatous polyposis (FAP) and one hereditary nonpolyposis colorectal cancer (HNPCC). Among the an- alyzed patients, four (2.67%) had synchronous and one (0.67%) had metachronous cancer. Conclusion: the incidence of synchronous and metachronous colorectal cancer was, respectively, 2.67% and 0.67%, results that corroborate those reported in international literature. Resumo: Introdução: pacientes com diagnóstico de câncer colorretal esporádico ou associado a sín- dromes correm risco de apresentar lesões sincrônicas ou metacrônicas. Embora seja rele- vante, há escassez de informações sobre o tema na literatura nacional. Objetivo: avaliar a incidência e o perfil epidemiológico dos pacientes com tumor colorretal sincrônico e metacrônico em um serviço de referência em proctologia do Rio Grande do Sul. Método: estudo observacional transversal, realizado entre janeiro e julho de 2012, avaliando-se pacientes atendidos no serviço que preencheram os critérios de inclusão. Revisaram-se os prontuários, registrando-se variáveis demográficas, comorbidades e variáveis relacionadas ao tumor. Resultados: analisaram-se 150 prontuários, sendo 53,3% do sexo masculino com média de idade de 63 (+13,01) anos. A topografia mais incidente foi cólon sigmoide e reto alto (50,67%) seguido do reto baixo (36%). O adenocarcinoma foi o subtipo histológico mais prevalente (88%) seguido pelo epidermoide (1,33%). Síndromes hereditárias foram identificadas em cinco pacientes (3,33%), sendo quatro com polipose adenomatosa familiar e um paciente com câncer colorretal hereditário não polipose. Dos 150 pacientes, quatro (2,67%) apresen- taram neoplasia sincrônica e um (0,67%) lesão metacrônica. Conclusão: a incidência de tu- mor colorretal sincrônico e metacrônico na população avaliada foi, respectivamente, 2,67% e 0,67%, resultados que corroboram achados da literatura estrangeira. Keywords: Colonic neoplasms, Colorectal neoplasms, Colorectal surgery, Epidemiology, Surgery, Palavras-chave: Neoplasias de cólon, Neoplasias colorretais, Cirurgia colorretal, Epidemiologia, Cirurgiahttp://www.sciencedirect.com/science/article/pii/S223793631300021X
collection DOAJ
language English
format Article
sources DOAJ
author Eduardo Brambilla
Augusto Cardoso Sgarioni
Guilherme Finger
Guilherme Sartori
Maicon Joel Cimarosti
spellingShingle Eduardo Brambilla
Augusto Cardoso Sgarioni
Guilherme Finger
Guilherme Sartori
Maicon Joel Cimarosti
Incidence and epidemiological features of synchronous and metachronous colorectal cancer
Journal of Coloproctology
author_facet Eduardo Brambilla
Augusto Cardoso Sgarioni
Guilherme Finger
Guilherme Sartori
Maicon Joel Cimarosti
author_sort Eduardo Brambilla
title Incidence and epidemiological features of synchronous and metachronous colorectal cancer
title_short Incidence and epidemiological features of synchronous and metachronous colorectal cancer
title_full Incidence and epidemiological features of synchronous and metachronous colorectal cancer
title_fullStr Incidence and epidemiological features of synchronous and metachronous colorectal cancer
title_full_unstemmed Incidence and epidemiological features of synchronous and metachronous colorectal cancer
title_sort incidence and epidemiological features of synchronous and metachronous colorectal cancer
publisher Thieme Revinter Publicações Ltda.
series Journal of Coloproctology
issn 2237-9363
publishDate 2013-04-01
description Introduction: patients with sporadic colorectal cancer or cases associated with syndromes are at risk of having synchronous or metachronous cancer. Although it is an important subject, Brazilian data on the subject are scarce. Objective: to evaluate the incidence and epidemiological features in patients with synchro- nous and metachronous colorectal cancer in a reference service of proctology in the Rio Grande do Sul. Methods: cross-sectional observational study, performed between January and July 2012, analyzing all patients admitted in the service that met the inclusion criteria. A retrospective review of records was performed, noting demographic variables, comorbidi- ties and tumor-related variables. Results: 150 records were analyzed, of which 53.3% were males and mean age was 63 (± 13.01) years old. The most frequently found tumor location was the sigmoid colon and high rectum (50.67%), followed by the lower rectum (36%). Adenocarcinomas were the most prevalent histological subtype (88%), followed by epidermoid tumors (1.33%). Hereditary syndromes were identified in five patients (3.33%), with four being Familial adenomatous polyposis (FAP) and one hereditary nonpolyposis colorectal cancer (HNPCC). Among the an- alyzed patients, four (2.67%) had synchronous and one (0.67%) had metachronous cancer. Conclusion: the incidence of synchronous and metachronous colorectal cancer was, respectively, 2.67% and 0.67%, results that corroborate those reported in international literature. Resumo: Introdução: pacientes com diagnóstico de câncer colorretal esporádico ou associado a sín- dromes correm risco de apresentar lesões sincrônicas ou metacrônicas. Embora seja rele- vante, há escassez de informações sobre o tema na literatura nacional. Objetivo: avaliar a incidência e o perfil epidemiológico dos pacientes com tumor colorretal sincrônico e metacrônico em um serviço de referência em proctologia do Rio Grande do Sul. Método: estudo observacional transversal, realizado entre janeiro e julho de 2012, avaliando-se pacientes atendidos no serviço que preencheram os critérios de inclusão. Revisaram-se os prontuários, registrando-se variáveis demográficas, comorbidades e variáveis relacionadas ao tumor. Resultados: analisaram-se 150 prontuários, sendo 53,3% do sexo masculino com média de idade de 63 (+13,01) anos. A topografia mais incidente foi cólon sigmoide e reto alto (50,67%) seguido do reto baixo (36%). O adenocarcinoma foi o subtipo histológico mais prevalente (88%) seguido pelo epidermoide (1,33%). Síndromes hereditárias foram identificadas em cinco pacientes (3,33%), sendo quatro com polipose adenomatosa familiar e um paciente com câncer colorretal hereditário não polipose. Dos 150 pacientes, quatro (2,67%) apresen- taram neoplasia sincrônica e um (0,67%) lesão metacrônica. Conclusão: a incidência de tu- mor colorretal sincrônico e metacrônico na população avaliada foi, respectivamente, 2,67% e 0,67%, resultados que corroboram achados da literatura estrangeira. Keywords: Colonic neoplasms, Colorectal neoplasms, Colorectal surgery, Epidemiology, Surgery, Palavras-chave: Neoplasias de cólon, Neoplasias colorretais, Cirurgia colorretal, Epidemiologia, Cirurgia
url http://www.sciencedirect.com/science/article/pii/S223793631300021X
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