Development and Standardization of a High-Throughput Multiplex Immunoassay for the Simultaneous Quantification of Specific Antibodies to Five Respiratory Syncytial Virus Proteins

Development and Standardization of a High-Throughput Multiplex Immunoassay for the Simultaneous Quantification of Specific Antibodies to Five Respiratory Syncytial Virus Proteins

In view of vaccine and monoclonal development to reduce hospitalization and death due to lower respiratory tract infection caused by RSV, assessment of antibody levels against RSV is essential. This newly developed multiplex immunoassay is able to measure antibody levels against five RSV proteins si...

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Bibliographic Details
Main Authors: Rutger M. Schepp, Cornelis A. M. de Haan, Deidre Wilkins, Hans Layman, Barney S. Graham, Mark T. Esser, Guy A. M. Berbers
Format: Article
Language:English
Published: American Society for Microbiology 2019-04-01
Series:mSphere
Subjects:
assay development
immunoassays
multiplex
respiratory syncytial virus
Online Access:https://doi.org/10.1128/mSphere.00236-19

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