Sequence variability at the internal ribosome entry site of the HCV genome in relation to therapy outcome

Sequence variability at the internal ribosome entry site of the HCV genome in relation to therapy outcome

Different types of interferon are widely used to treat hepatitis C virus (HCV) infection. Results obtained in vitro suggest that interferon inhibits internal ribosome entry site (IRES)-mediated translation of the HCV genome. To elucidate the possible effect of the nucleotide sequence of IRES on ther...

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Bibliographic Details
Main Authors: Jovanović-Ćupić Snežana, Simonović-Babić Jasmina, Blagojević Jelena, Božić Milena, Ješić Rada, Nožić D., Stamenković Gorana
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2009-01-01
Series:Archives of Biological Sciences
Subjects:
hepatitis C virus
interferon
internal ribosome entry site
genotypes 1b and 3a
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2009/0354-46640902205J.pdf

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