Exendin-4 Promotes Beta Cell Proliferation via PI3k/Akt Signalling Pathway

Exendin-4 Promotes Beta Cell Proliferation via PI3k/Akt Signalling Pathway

Background/Aims: Prevention of diabetes requires maintenance of a functional beta-cell mass, the postnatal growth of which depends on beta cell proliferation. Past studies have shown evidence of an effect of an incretin analogue, Exendin-4, in promoting beta cell proliferation, whereas the underlyin...

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Bibliographic Details
Main Authors: Chaoxun Wang, Xiaopan Chen, Xiaoying Ding, Yanju He, Chengying Gu, Ligang Zhou
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-04-01
Series:Cellular Physiology and Biochemistry
Subjects:
Exendin-4
Incretin
Diabetes
PI3k/Akt
Beta-cell proliferation
Online Access:http://www.karger.com/Article/FullText/374027

Internet

http://www.karger.com/Article/FullText/374027

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