Mediastinal mass in an tuberculosis-exposed 2-year old child with neurofibromatosis type 1 – TB or not TB?

Mediastinal mass in an tuberculosis-exposed 2-year old child with neurofibromatosis type 1 – TB or not TB?

A toddler with neurofibromatosis type 1 (NF1) was evaluated for tuberculosis (TB) after exposure. Chest X-ray (CXR) revealed a mediastinal mass indicating lymphadenopathy. However, magnetic resonance imaging showed a large plexiform thoracic neurofibroma.CXR performed for TB screening in NF1 patient...

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Bibliographic Details
Main Authors: Renate Krüger, Cornelia Potratz, Pablo Hernáiz-Driever, Birgit Lala, Cornelia Feiterna-Sperling
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Respiratory Medicine Case Reports
Subjects:
Neurofibromatosis
Tuberculosis
Mediastinal mass
Children
Online Access:http://www.sciencedirect.com/science/article/pii/S2213007120305384
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spelling doaj-5bcd214ef005490a89facdc5eb538e252021-03-22T12:49:46ZengElsevierRespiratory Medicine Case Reports2213-00712021-01-0132101324Mediastinal mass in an tuberculosis-exposed 2-year old child with neurofibromatosis type 1 – TB or not TB?Renate Krüger0Cornelia Potratz1Pablo Hernáiz-Driever2Birgit Lala3Cornelia Feiterna-Sperling4Department of Pediatric Pneumonology, Immunology and Intensive Care Medicine, Charité - Universitätsmedizin, Berlin, GermanyDepartment of Pediatric Neurology, Charité - Universitätsmedizin, Berlin, GermanyDepartment of Pediatric Hematology and Oncology, Charité - Universitätsmedizin, Berlin, GermanyDepartment of Pediatric Radiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, GermanyDepartment of Pediatric Pneumonology, Immunology and Intensive Care Medicine, Charité - Universitätsmedizin, Berlin, Germany; Corresponding author. Department of Pediatric Pneumonology, Immunology and Intensive Care Medicine, Charité-Universitätsmedizin, Augustenburger Platz 1, 13353, Berlin, Germany.A toddler with neurofibromatosis type 1 (NF1) was evaluated for tuberculosis (TB) after exposure. Chest X-ray (CXR) revealed a mediastinal mass indicating lymphadenopathy. However, magnetic resonance imaging showed a large plexiform thoracic neurofibroma.CXR performed for TB screening in NF1 patients cannot clearly differentiate lymphadenopathy from thoracic plexiform neurofibroma. Cross sectional imaging is therefore indicated for classification of mediastinal masses.http://www.sciencedirect.com/science/article/pii/S2213007120305384NeurofibromatosisTuberculosisMediastinal massChildren
collection DOAJ
language English
format Article
sources DOAJ
author Renate Krüger
Cornelia Potratz
Pablo Hernáiz-Driever
Birgit Lala
Cornelia Feiterna-Sperling
spellingShingle Renate Krüger
Cornelia Potratz
Pablo Hernáiz-Driever
Birgit Lala
Cornelia Feiterna-Sperling
Mediastinal mass in an tuberculosis-exposed 2-year old child with neurofibromatosis type 1 – TB or not TB?
Respiratory Medicine Case Reports
Neurofibromatosis
Tuberculosis
Mediastinal mass
Children
author_facet Renate Krüger
Cornelia Potratz
Pablo Hernáiz-Driever
Birgit Lala
Cornelia Feiterna-Sperling
author_sort Renate Krüger
title Mediastinal mass in an tuberculosis-exposed 2-year old child with neurofibromatosis type 1 – TB or not TB?
title_short Mediastinal mass in an tuberculosis-exposed 2-year old child with neurofibromatosis type 1 – TB or not TB?
title_full Mediastinal mass in an tuberculosis-exposed 2-year old child with neurofibromatosis type 1 – TB or not TB?
title_fullStr Mediastinal mass in an tuberculosis-exposed 2-year old child with neurofibromatosis type 1 – TB or not TB?
title_full_unstemmed Mediastinal mass in an tuberculosis-exposed 2-year old child with neurofibromatosis type 1 – TB or not TB?
title_sort mediastinal mass in an tuberculosis-exposed 2-year old child with neurofibromatosis type 1 – tb or not tb?
publisher Elsevier
series Respiratory Medicine Case Reports
issn 2213-0071
publishDate 2021-01-01
description A toddler with neurofibromatosis type 1 (NF1) was evaluated for tuberculosis (TB) after exposure. Chest X-ray (CXR) revealed a mediastinal mass indicating lymphadenopathy. However, magnetic resonance imaging showed a large plexiform thoracic neurofibroma.CXR performed for TB screening in NF1 patients cannot clearly differentiate lymphadenopathy from thoracic plexiform neurofibroma. Cross sectional imaging is therefore indicated for classification of mediastinal masses.
topic Neurofibromatosis
Tuberculosis
Mediastinal mass
Children
url http://www.sciencedirect.com/science/article/pii/S2213007120305384
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AT corneliapotratz mediastinalmassinantuberculosisexposed2yearoldchildwithneurofibromatosistype1tbornottb
AT pablohernaizdriever mediastinalmassinantuberculosisexposed2yearoldchildwithneurofibromatosistype1tbornottb
AT birgitlala mediastinalmassinantuberculosisexposed2yearoldchildwithneurofibromatosistype1tbornottb
AT corneliafeiternasperling mediastinalmassinantuberculosisexposed2yearoldchildwithneurofibromatosistype1tbornottb
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