DedA Protein Relates to Action-Mechanism of Halicyclamine A, a Marine Spongean Macrocyclic Alkaloid, as an Anti-dormant Mycobacterial Substance

A macrocyclic alkaloid, halicyclamine A, was re-discovered from an Indonesian marine sponge of Haliclona sp. 05A08 as an anti-dormant mycobacterial substance. To clarify action-mechanism of halicyclamine A, halicyclamine A-resistant strains were screened from the transformants of Mycobacterium smegm...

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Bibliographic Details
Main Authors: Andi Setiawan, Motomasa Kobayashi, Takao Fujimoto, Liu Liu, Masayoshi Arai
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/9/6/984/