MiR-199a/b-3p inhibits gastric cancer cell proliferation via down-regulating PAK4/MEK/ERK signaling pathway

MiR-199a/b-3p inhibits gastric cancer cell proliferation via down-regulating PAK4/MEK/ERK signaling pathway

Abstract Background Gastric cancer (GC) is one of the most frequent malignant tumors and the molecular mechanism underlying its proliferation remains far from completely understood. Although accumulating evidence shows that abnormal expression of microRNA (miRNA) is involved in tumorigenesis, the ro...

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Bibliographic Details
Main Authors: Bin Zeng, Wei Shi, Gao Tan
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Cancer
Subjects:
MiR-199a/b-3p
Gastric cancer
PAK4
ERK
Online Access:http://link.springer.com/article/10.1186/s12885-017-3949-2

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