Early cortical thickness changes predict β-amyloid deposition in a mouse model of Alzheimer's disease

Early cortical thickness changes predict β-amyloid deposition in a mouse model of Alzheimer's disease

Magnetic resonance imaging (MRI) studies have identified aberrant cortical structure in Alzheimer's disease (AD). The association between MRI-derived cortical morphometry measures and β-amyloid, however, remains poorly understood. In this study, we explored the potential relationship between ea...

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Bibliographic Details
Main Authors: Marilyn Grand'Maison, Simone P. Zehntner, Ming-Kai Ho, François Hébert, Andrew Wood, Felix Carbonell, Alex P. Zijdenbos, Edith Hamel, Barry J. Bedell
Format: Article
Language:English
Published: Elsevier 2013-06-01
Series:Neurobiology of Disease
Subjects:
Alzheimer's disease
Animal model
Beta-amyloid
Cortical thickness
Quantitative immunohistochemistry
Magnetic resonance imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113000673

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