Dexmedetomidine Pretreatment Attenuates Kidney Injury and Oxidative Stress during Orthotopic Autologous Liver Transplantation in Rats

Dexmedetomidine Pretreatment Attenuates Kidney Injury and Oxidative Stress during Orthotopic Autologous Liver Transplantation in Rats

This paper aims to explore whether pretreatment with dexmedetomidine (Dex) has antioxidative and renal protective effects during orthotopic autologous liver transplantation (OALT) and its impact on nuclear factor erythroid 2-related factor 2 (Nrf2) activation. Sprague-Dawley rats were randomized int...

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Bibliographic Details
Main Authors:	Xiaofang Yu, Xinjin Chi, Shan Wu, Yi Jin, Hui Yao, Yiheng Wang, Zhengyuan Xia, Jun Cai
Format:	Article
Language:	English
Published:	Hindawi Limited 2016-01-01
Series:	Oxidative Medicine and Cellular Longevity
Online Access:	http://dx.doi.org/10.1155/2016/4675817

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