Tumors: Too sweet to remember?

<p>Abstract</p> <p>Immunity, based on a natural and an educated system, is responsible for recognition and elimination of infectious particles, cellular waste, modified self and transformed cells. This dual system guarantees that dangerous particles are removed immediately after ap...

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Main Authors: Brändlein Stephanie, Vollmers H Peter
Format: Article
Language:English
Published: BMC 2007-12-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/6/1/78
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spelling doaj-5bae1eb13a14499c812247d026744ece2020-11-24T21:49:13ZengBMCMolecular Cancer1476-45982007-12-01617810.1186/1476-4598-6-78Tumors: Too sweet to remember?Brändlein StephanieVollmers H Peter<p>Abstract</p> <p>Immunity, based on a natural and an educated system, is responsible for recognition and elimination of infectious particles, cellular waste, modified self and transformed cells. This dual system guarantees that dangerous particles are removed immediately after appearance and that a memory with maturated weapons exists, if the organism is re-infected by the same particle. For malignant cells, however, the immune response seems to be restricted to innate immunity, because at least for the humoral response, all so far detected tumor-specific antibodies belong to the natural immunity. In this review we try to explain why malignant cells might be "too sweet" to induce a memory.</p> http://www.molecular-cancer.com/content/6/1/78
collection DOAJ
language English
format Article
sources DOAJ
author Brändlein Stephanie
Vollmers H Peter
spellingShingle Brändlein Stephanie
Vollmers H Peter
Tumors: Too sweet to remember?
Molecular Cancer
author_facet Brändlein Stephanie
Vollmers H Peter
author_sort Brändlein Stephanie
title Tumors: Too sweet to remember?
title_short Tumors: Too sweet to remember?
title_full Tumors: Too sweet to remember?
title_fullStr Tumors: Too sweet to remember?
title_full_unstemmed Tumors: Too sweet to remember?
title_sort tumors: too sweet to remember?
publisher BMC
series Molecular Cancer
issn 1476-4598
publishDate 2007-12-01
description <p>Abstract</p> <p>Immunity, based on a natural and an educated system, is responsible for recognition and elimination of infectious particles, cellular waste, modified self and transformed cells. This dual system guarantees that dangerous particles are removed immediately after appearance and that a memory with maturated weapons exists, if the organism is re-infected by the same particle. For malignant cells, however, the immune response seems to be restricted to innate immunity, because at least for the humoral response, all so far detected tumor-specific antibodies belong to the natural immunity. In this review we try to explain why malignant cells might be "too sweet" to induce a memory.</p>
url http://www.molecular-cancer.com/content/6/1/78
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