Tumors: Too sweet to remember?
<p>Abstract</p> <p>Immunity, based on a natural and an educated system, is responsible for recognition and elimination of infectious particles, cellular waste, modified self and transformed cells. This dual system guarantees that dangerous particles are removed immediately after ap...
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doaj-5bae1eb13a14499c812247d026744ece2020-11-24T21:49:13ZengBMCMolecular Cancer1476-45982007-12-01617810.1186/1476-4598-6-78Tumors: Too sweet to remember?Brändlein StephanieVollmers H Peter<p>Abstract</p> <p>Immunity, based on a natural and an educated system, is responsible for recognition and elimination of infectious particles, cellular waste, modified self and transformed cells. This dual system guarantees that dangerous particles are removed immediately after appearance and that a memory with maturated weapons exists, if the organism is re-infected by the same particle. For malignant cells, however, the immune response seems to be restricted to innate immunity, because at least for the humoral response, all so far detected tumor-specific antibodies belong to the natural immunity. In this review we try to explain why malignant cells might be "too sweet" to induce a memory.</p> http://www.molecular-cancer.com/content/6/1/78 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Brändlein Stephanie Vollmers H Peter |
spellingShingle |
Brändlein Stephanie Vollmers H Peter Tumors: Too sweet to remember? Molecular Cancer |
author_facet |
Brändlein Stephanie Vollmers H Peter |
author_sort |
Brändlein Stephanie |
title |
Tumors: Too sweet to remember? |
title_short |
Tumors: Too sweet to remember? |
title_full |
Tumors: Too sweet to remember? |
title_fullStr |
Tumors: Too sweet to remember? |
title_full_unstemmed |
Tumors: Too sweet to remember? |
title_sort |
tumors: too sweet to remember? |
publisher |
BMC |
series |
Molecular Cancer |
issn |
1476-4598 |
publishDate |
2007-12-01 |
description |
<p>Abstract</p> <p>Immunity, based on a natural and an educated system, is responsible for recognition and elimination of infectious particles, cellular waste, modified self and transformed cells. This dual system guarantees that dangerous particles are removed immediately after appearance and that a memory with maturated weapons exists, if the organism is re-infected by the same particle. For malignant cells, however, the immune response seems to be restricted to innate immunity, because at least for the humoral response, all so far detected tumor-specific antibodies belong to the natural immunity. In this review we try to explain why malignant cells might be "too sweet" to induce a memory.</p> |
url |
http://www.molecular-cancer.com/content/6/1/78 |
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AT brandleinstephanie tumorstoosweettoremember AT vollmershpeter tumorstoosweettoremember |
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