Anacardic Acids from <i>Amphipterygium adstringens</i> Confer Cytoprotection against 5-Fluorouracil and Carboplatin Induced Blood Cell Toxicity While Increasing Antitumoral Activity and Survival in an Animal Model of Breast Cancer

Anacardic Acids from <i>Amphipterygium adstringens</i> Confer Cytoprotection against 5-Fluorouracil and Carboplatin Induced Blood Cell Toxicity While Increasing Antitumoral Activity and Survival in an Animal Model of Breast Cancer

<i>Amphipterygium adstringens</i> (cuachalalate) contains anacardic acids (AAs) such as 6-pentadecyl salicylic acid (6SA) that show immunomodulatory and antitumor activity with minimal or no secondary adverse effects. By contrast, most chemotherapeutic agents, such as 5-fluorouracil (5-F...

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Bibliographic Details
Main Authors: Jairo Galot-Linaldi, Karla M. Hernández-Sánchez, Elizabet Estrada-Muñiz, Libia Vega
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Molecules
Subjects:
<i>Amphiterygium adstringens</i>
anacardic acids
myeloprotective
antineoplastic agent
autologous tumor model
Online Access:https://www.mdpi.com/1420-3049/26/11/3241

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