Monte Carlo analysis of neck linker extension in kinesin molecular motors.

Kinesin stepping is thought to involve both concerted conformational changes and diffusive movement, but the relative roles played by these two processes are not clear. The neck linker docking model is widely accepted in the field, but the remainder of the step--diffusion of the tethered head to the...

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Bibliographic Details
Main Authors: Matthew L Kutys, John Fricks, William O Hancock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2973807?pdf=render

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