Comparison of novel and existing methods for detecting differentially methylated regions

Comparison of novel and existing methods for detecting differentially methylated regions

Abstract Background Single-probe analyses in epigenome-wide association studies (EWAS) have identified associations between DNA methylation and many phenotypes, but do not take into account information from neighboring probes. Methods to detect differentially methylated regions (DMRs) (clusters of n...

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Bibliographic Details
Main Authors: Samantha Lent, Hanfei Xu, Lan Wang, Zhe Wang, Chloé Sarnowski, Marie-France Hivert, Josée Dupuis
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Genetics
Subjects:
Epigenetics
DNA methylation
Differentially methylated regions
Online Access:http://link.springer.com/article/10.1186/s12863-018-0637-4

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