LncRNA TUBA4B functions as a competitive endogenous RNA to inhibit gastric cancer progression by elevating PTEN via sponging miR-214 and miR-216a/b

LncRNA TUBA4B functions as a competitive endogenous RNA to inhibit gastric cancer progression by elevating PTEN via sponging miR-214 and miR-216a/b

Abstract Background Emerging evidence demonstrates that long non-coding RNA (lncRNA) is an important regulator in tumorigenesis and development. Tubulin Alpha 4B (TUBA4B), a novel lncRNA, was recently proposed as a tumor suppressor in several human cancers. However, its role in gastric cancer (GC) r...

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Bibliographic Details
Main Authors: Jianbo Guo, Yan Li, He Duan, Lu Yuan
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Cancer Cell International
Subjects:
Long non-coding RNA
TUBA4B
Gastric cancer
ceRNA
PI3K/AKT signaling
Biomarker
Online Access:http://link.springer.com/article/10.1186/s12935-019-0879-x

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http://link.springer.com/article/10.1186/s12935-019-0879-x

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