[PSI+] maintenance is dependent on the composition, not primary sequence, of the oligopeptide repeat domain.

[PSI+] maintenance is dependent on the composition, not primary sequence, of the oligopeptide repeat domain.

[PSI(+)], the prion form of the yeast Sup35 protein, results from the structural conversion of Sup35 from a soluble form into an infectious amyloid form. The infectivity of prions is thought to result from chaperone-dependent fiber cleavage that breaks large prion fibers into smaller, inheritable pr...

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Bibliographic Details
Main Authors: James A Toombs, Nathan M Liss, Kacy R Cobble, Zobaida Ben-Musa, Eric D Ross
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3132755?pdf=render

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