Visfatin Increases VEGF-dependent Angiogenesis of Endothelial Progenitor Cells during Osteoarthritis Progression

Visfatin Increases VEGF-dependent Angiogenesis of Endothelial Progenitor Cells during Osteoarthritis Progression

Osteoarthritis (OA) pannus contains a network of neovascularization that is formed and maintained by angiogenesis, which is promoted by vascular endothelial growth factor (VEGF). Bone marrow-derived endothelial progenitor cells (EPCs) are involved in VEGF-induced vessel formation in OA. The adipokin...

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Bibliographic Details
Main Authors: Chun-Hao Tsai, Shan-Chi Liu, Wen-Hui Chung, Shih-Wei Wang, Min-Huan Wu, Chih-Hsin Tang
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
osteoarthritis
visfatin
VEGF
miR-485-5p
angiogenesis
Online Access:https://www.mdpi.com/2073-4409/9/5/1315

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