Reduction of Duration of Antibiotic Therapy for Suspected Early-Onset Sepsis in Late-Preterm and Term Newborns After Implementation of a Procalcitonin-Guided Algorithm: A Population-Based Study in Central Switzerland

Reduction of Duration of Antibiotic Therapy for Suspected Early-Onset Sepsis in Late-Preterm and Term Newborns After Implementation of a Procalcitonin-Guided Algorithm: A Population-Based Study in Central Switzerland

Background: Suspected early-onset sepsis (EOS) is the main reason for antibiotic therapy at the start of life. Prolonged antibiotic therapy for culture-negative sepsis is often reported. Antibiotic stewardship is mandatory due to the potential negative effects of unnecessary antibiotics. Procalciton...

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Bibliographic Details
Main Authors: Jennifer Zihlmann-Ji, Christian Braun, Michael Buettcher, Markus Hodel, Dirk Lehnick, Martin Stocker
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pediatrics
Subjects:
early-onset sepsis
antibiotic stewardship
procalcitonin
neonates
biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2021.702133/full

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