PDGF-B Is Required for Development of the Glymphatic System

Summary: The glymphatic system is a highly polarized cerebrospinal fluid (CSF) transport system that facilitates the clearance of neurotoxic molecules through a brain-wide network of perivascular pathways. Herein we have mapped the development of the glymphatic system in mice. Perivascular CSF trans...

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Bibliographic Details
Main Authors: Anne Sofie Munk, Wei Wang, Nicholas Burdon Bèchet, Ahmed M. Eltanahy, Anne Xiaoan Cheng, Björn Sigurdsson, Abdellatif Benraiss, Maarja A. Mäe, Benjamin Travis Kress, Douglas H. Kelley, Christer Betsholtz, Kjeld Møllgård, Anja Meissner, Maiken Nedergaard, Iben Lundgaard
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719302293