Pharmacodynamic effects of C-domain-specific ACE inhibitors on the renin-angiotensin system in myocardial infarcted rats

Introduction: The renin-angiotensin system (RAS) is a dynamic network that plays a critical role in blood pressure regulation and fluid and electrolyte homeostasis. Modulators of the RAS, such as angiotensin-converting enzyme (ACE) inhibitors, are widely used to treat hypertension, heart failure and...

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Bibliographic Details
Main Authors: Sarah Sharp, Marko Poglitsch, Peter Zilla, Neil H Davies, Edward D Sturrock
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2015-12-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.1177/1470320314568438