Microwave assisted synthesis of imidazolyl fluorescent dyes as antimicrobial agents

Microwave assisted synthesis of imidazolyl fluorescent dyes as antimicrobial agents

In this article, we report, the synthesis and characterization of series of novel fluorescent imidazolyl dyes (5a-d) via highly efficient and cost-effective microwave assisted protocol as a potential candidate to overcome the problem of microbial resistance. By utilizing the green microwave protocol...

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Main Authors: Chinna Bathula, Ravindra MK, Ashok Kumar K, Hemraj Yadav, Sivalingam Ramesh, Surendra Shinde, Nabeen K Shrestha, Mahadevan KM, Veeranjaneya Reddy, Arifullah Mohammed
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Journal of Materials Research and Technology
Subjects:
Imidazole
Florescent dyes
Microwave reaction
Antimicrobial agents
Online Access:http://www.sciencedirect.com/science/article/pii/S2238785419319544
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spelling doaj-5b4f766ea69946a39e6f6bf871ae7e642020-11-25T01:25:10ZengElsevierJournal of Materials Research and Technology2238-78542020-05-019369006908Microwave assisted synthesis of imidazolyl fluorescent dyes as antimicrobial agentsChinna Bathula0Ravindra MK1Ashok Kumar K2Hemraj Yadav3Sivalingam Ramesh4Surendra Shinde5Nabeen K Shrestha6Mahadevan KM7Veeranjaneya Reddy8Arifullah Mohammed9Division of Electronics and Electrical Engineering, Dongguk University-Seoul, Seoul 04620, Republic of KoreaDepartment of Chemistry, Kuvempu University, P. G. Centre Kadur-577548, IndiaDepartment of Energy and Materials Engineering, Dongguk University-Seoul, Seoul 04620, Republic of KoreaDepartment of Energy and Materials Engineering, Dongguk University-Seoul, Seoul 04620, Republic of KoreaDepartment of Mechanical, Robotics and Energy Engineering, Dongguk University-Seoul, Seoul 04620, Republic of KoreaDepartment of Biological and Environmental Science, Dongguk University, Biomedical Campus, Ilsandong, 10326, Republic of KoreaDivision of Physics and Semiconductor Science, Dongguk University-Seoul, Seoul 04620, Republic of KoreaDepartment of Chemistry, Kuvempu University, P. G. Centre Kadur-577548, India; Corresponding authors.Department of Food Science and Technology, Yeungnam University, Gyeongsan 712-749, Republic of Korea; Department of Microbiology, Yogi Vemana University, Kadapa (A.P.) 516003, India; Corresponding authors.Faculty of Agro Based Industry, Institute of Food Security and Sustainable Agriculture(IFSSA), Universiti Malaysia Kelantan Campus, Jeli 17600, Malaysia; Corresponding authors.In this article, we report, the synthesis and characterization of series of novel fluorescent imidazolyl dyes (5a-d) via highly efficient and cost-effective microwave assisted protocol as a potential candidate to overcome the problem of microbial resistance. By utilizing the green microwave protocol the reactions are completed in a short span of time without using the harsh conditions. The incorporation of imidazole nucleus is an important strategy in drug discovery. While designing desired fluorescent imidazole dyes 5a-d, with a suitable auxiliary donor such as aromatic rings and −OCH3 group on one end of the imidazolyl moiety and electron acceptors such as -NO2 and −COOH on other end of the compounds was achieved to get a promising fluorescent dyes for antimicrobial. The optoelectronic properties and antimicrobial studies of the synthesized materials indicated their exploration as a promising candidate as antimicrobial agents.http://www.sciencedirect.com/science/article/pii/S2238785419319544ImidazoleFlorescent dyesMicrowave reactionAntimicrobial agents
collection DOAJ
language English
format Article
sources DOAJ
author Chinna Bathula
Ravindra MK
Ashok Kumar K
Hemraj Yadav
Sivalingam Ramesh
Surendra Shinde
Nabeen K Shrestha
Mahadevan KM
Veeranjaneya Reddy
Arifullah Mohammed
spellingShingle Chinna Bathula
Ravindra MK
Ashok Kumar K
Hemraj Yadav
Sivalingam Ramesh
Surendra Shinde
Nabeen K Shrestha
Mahadevan KM
Veeranjaneya Reddy
Arifullah Mohammed
Microwave assisted synthesis of imidazolyl fluorescent dyes as antimicrobial agents
Journal of Materials Research and Technology
Imidazole
Florescent dyes
Microwave reaction
Antimicrobial agents
author_facet Chinna Bathula
Ravindra MK
Ashok Kumar K
Hemraj Yadav
Sivalingam Ramesh
Surendra Shinde
Nabeen K Shrestha
Mahadevan KM
Veeranjaneya Reddy
Arifullah Mohammed
author_sort Chinna Bathula
title Microwave assisted synthesis of imidazolyl fluorescent dyes as antimicrobial agents
title_short Microwave assisted synthesis of imidazolyl fluorescent dyes as antimicrobial agents
title_full Microwave assisted synthesis of imidazolyl fluorescent dyes as antimicrobial agents
title_fullStr Microwave assisted synthesis of imidazolyl fluorescent dyes as antimicrobial agents
title_full_unstemmed Microwave assisted synthesis of imidazolyl fluorescent dyes as antimicrobial agents
title_sort microwave assisted synthesis of imidazolyl fluorescent dyes as antimicrobial agents
publisher Elsevier
series Journal of Materials Research and Technology
issn 2238-7854
publishDate 2020-05-01
description In this article, we report, the synthesis and characterization of series of novel fluorescent imidazolyl dyes (5a-d) via highly efficient and cost-effective microwave assisted protocol as a potential candidate to overcome the problem of microbial resistance. By utilizing the green microwave protocol the reactions are completed in a short span of time without using the harsh conditions. The incorporation of imidazole nucleus is an important strategy in drug discovery. While designing desired fluorescent imidazole dyes 5a-d, with a suitable auxiliary donor such as aromatic rings and −OCH3 group on one end of the imidazolyl moiety and electron acceptors such as -NO2 and −COOH on other end of the compounds was achieved to get a promising fluorescent dyes for antimicrobial. The optoelectronic properties and antimicrobial studies of the synthesized materials indicated their exploration as a promising candidate as antimicrobial agents.
topic Imidazole
Florescent dyes
Microwave reaction
Antimicrobial agents
url http://www.sciencedirect.com/science/article/pii/S2238785419319544
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