Cytoskeleton actin changes in IL-2 activated cells

In the present study we analysed the changes in cytoskeletal actin in lymphoid cells following IL-2 activation and during cell interactions by means of light and electron microscopy, immunofluorescence and molecular analysis. By morphological analysis we observed a higher fluorescence in the activat...

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Main Authors: E Capelli, R Nano, S Panelli, L Sciola, A Spano, S Barni
Format: Article
Language:English
Published: PAGEPress Publications 2009-12-01
Series:European Journal of Histochemistry
Online Access:https://www.ejh.it/index.php/ejh/article/view/1591
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spelling doaj-5b4e38303c2e494d90553d99ebd1b7502021-09-24T06:52:22ZengPAGEPress PublicationsEuropean Journal of Histochemistry 1121-760X2038-83062009-12-0144310.4081/ejh.2000.1591Cytoskeleton actin changes in IL-2 activated cellsE Capelli0R NanoS PanelliL SciolaA SpanoS BarniPAGEPress Office, PaviaIn the present study we analysed the changes in cytoskeletal actin in lymphoid cells following IL-2 activation and during cell interactions by means of light and electron microscopy, immunofluorescence and molecular analysis. By morphological analysis we observed a higher fluorescence in the activated cells than in the quiescent ones with no modifications in the cytoskeleton pattern comparing activated to resting cells. The results of molecular analysis indicate that, after IL-2 activation, there is a reorganisation of the actin component of the cell cytoskeleton accompanied by the differential expression of the corresponding genes. A future study will be extended to the analysis of others components of the cytoskeleton network.https://www.ejh.it/index.php/ejh/article/view/1591
collection DOAJ
language English
format Article
sources DOAJ
author E Capelli
R Nano
S Panelli
L Sciola
A Spano
S Barni
spellingShingle E Capelli
R Nano
S Panelli
L Sciola
A Spano
S Barni
Cytoskeleton actin changes in IL-2 activated cells
European Journal of Histochemistry
author_facet E Capelli
R Nano
S Panelli
L Sciola
A Spano
S Barni
author_sort E Capelli
title Cytoskeleton actin changes in IL-2 activated cells
title_short Cytoskeleton actin changes in IL-2 activated cells
title_full Cytoskeleton actin changes in IL-2 activated cells
title_fullStr Cytoskeleton actin changes in IL-2 activated cells
title_full_unstemmed Cytoskeleton actin changes in IL-2 activated cells
title_sort cytoskeleton actin changes in il-2 activated cells
publisher PAGEPress Publications
series European Journal of Histochemistry
issn 1121-760X
2038-8306
publishDate 2009-12-01
description In the present study we analysed the changes in cytoskeletal actin in lymphoid cells following IL-2 activation and during cell interactions by means of light and electron microscopy, immunofluorescence and molecular analysis. By morphological analysis we observed a higher fluorescence in the activated cells than in the quiescent ones with no modifications in the cytoskeleton pattern comparing activated to resting cells. The results of molecular analysis indicate that, after IL-2 activation, there is a reorganisation of the actin component of the cell cytoskeleton accompanied by the differential expression of the corresponding genes. A future study will be extended to the analysis of others components of the cytoskeleton network.
url https://www.ejh.it/index.php/ejh/article/view/1591
work_keys_str_mv AT ecapelli cytoskeletonactinchangesinil2activatedcells
AT rnano cytoskeletonactinchangesinil2activatedcells
AT spanelli cytoskeletonactinchangesinil2activatedcells
AT lsciola cytoskeletonactinchangesinil2activatedcells
AT aspano cytoskeletonactinchangesinil2activatedcells
AT sbarni cytoskeletonactinchangesinil2activatedcells
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