Cytoskeleton actin changes in IL-2 activated cells
In the present study we analysed the changes in cytoskeletal actin in lymphoid cells following IL-2 activation and during cell interactions by means of light and electron microscopy, immunofluorescence and molecular analysis. By morphological analysis we observed a higher fluorescence in the activat...
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2009-12-01
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Series: | European Journal of Histochemistry |
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doaj-5b4e38303c2e494d90553d99ebd1b7502021-09-24T06:52:22ZengPAGEPress PublicationsEuropean Journal of Histochemistry 1121-760X2038-83062009-12-0144310.4081/ejh.2000.1591Cytoskeleton actin changes in IL-2 activated cellsE Capelli0R NanoS PanelliL SciolaA SpanoS BarniPAGEPress Office, PaviaIn the present study we analysed the changes in cytoskeletal actin in lymphoid cells following IL-2 activation and during cell interactions by means of light and electron microscopy, immunofluorescence and molecular analysis. By morphological analysis we observed a higher fluorescence in the activated cells than in the quiescent ones with no modifications in the cytoskeleton pattern comparing activated to resting cells. The results of molecular analysis indicate that, after IL-2 activation, there is a reorganisation of the actin component of the cell cytoskeleton accompanied by the differential expression of the corresponding genes. A future study will be extended to the analysis of others components of the cytoskeleton network.https://www.ejh.it/index.php/ejh/article/view/1591 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
E Capelli R Nano S Panelli L Sciola A Spano S Barni |
spellingShingle |
E Capelli R Nano S Panelli L Sciola A Spano S Barni Cytoskeleton actin changes in IL-2 activated cells European Journal of Histochemistry |
author_facet |
E Capelli R Nano S Panelli L Sciola A Spano S Barni |
author_sort |
E Capelli |
title |
Cytoskeleton actin changes in IL-2 activated cells |
title_short |
Cytoskeleton actin changes in IL-2 activated cells |
title_full |
Cytoskeleton actin changes in IL-2 activated cells |
title_fullStr |
Cytoskeleton actin changes in IL-2 activated cells |
title_full_unstemmed |
Cytoskeleton actin changes in IL-2 activated cells |
title_sort |
cytoskeleton actin changes in il-2 activated cells |
publisher |
PAGEPress Publications |
series |
European Journal of Histochemistry |
issn |
1121-760X 2038-8306 |
publishDate |
2009-12-01 |
description |
In the present study we analysed the changes in cytoskeletal actin in lymphoid cells following IL-2 activation and during cell interactions by means of light and electron microscopy, immunofluorescence and molecular analysis. By morphological analysis we observed a higher fluorescence in the activated cells than in the quiescent ones with no modifications in the cytoskeleton pattern comparing activated to resting cells. The results of molecular analysis indicate that, after IL-2 activation, there is a reorganisation of the actin component of the cell cytoskeleton accompanied by the differential expression of the corresponding genes. A future study will be extended to the analysis of others components of the cytoskeleton network. |
url |
https://www.ejh.it/index.php/ejh/article/view/1591 |
work_keys_str_mv |
AT ecapelli cytoskeletonactinchangesinil2activatedcells AT rnano cytoskeletonactinchangesinil2activatedcells AT spanelli cytoskeletonactinchangesinil2activatedcells AT lsciola cytoskeletonactinchangesinil2activatedcells AT aspano cytoskeletonactinchangesinil2activatedcells AT sbarni cytoskeletonactinchangesinil2activatedcells |
_version_ |
1717370105297371136 |