Single cell transcriptional zonation of human psoriasis skin identifies an alternative immunoregulatory axis conducted by skin resident cells

Abstract Psoriasis is the most common skin disease in adults. Current experimental and clinical evidences suggested the infiltrating immune cells could target local skin cells and thus induce psoriatic phenotype. However, recent studies indicated the existence of a potential feedback signaling loop...

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Bibliographic Details
Main Authors: Yuge Gao, Xinyu Yao, Yumeng Zhai, Li Li, Huini Li, Xianqi Sun, Pei Yu, Tiankuo Xue, Yuzhen Li, Yizhou Hu
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03724-6