Aligned fibrin/functionalized self-assembling peptide interpenetrating nanofiber hydrogel presenting multi-cues promotes peripheral nerve functional recovery

Aligned fibrin/functionalized self-assembling peptide interpenetrating nanofiber hydrogel presenting multi-cues promotes peripheral nerve functional recovery

Nerve guidance conduits with hollow lumen fail to regenerate critical-sized peripheral nerve defects (15 mm in rats and 25 mm in humans), which can be improved by a beneficial intraluminal microenvironment. However, individual cues provided by intraluminal filling materials are inadequate to elimina...

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Bibliographic Details
Main Authors: Shuhui Yang, Jinjin Zhu, Changfeng Lu, Yi Chai, Zheng Cao, Jiaju Lu, Zhe Zhang, He Zhao, Yin-Yuan Huang, Shenglian Yao, Xiangdong Kong, Peixun Zhang, Xiumei Wang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2022-02-01
Series:Bioactive Materials
Subjects:
Peripheral nerve regeneration
Alignment
Nanofibers
Fibrin
Self-assembling peptides
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21002772

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http://www.sciencedirect.com/science/article/pii/S2452199X21002772

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