Preliminary pharmacological activity of the methanolic extract of Premna integrifolia barks in rats

Preliminary pharmacological activity of the methanolic extract of Premna integrifolia barks in rats

Objective: Premna integrifolia Linn (Family: Verbenaceae) synonym of Premna serratifolia has tremendous medicinal value. Preliminary pharmacological studies were performed on the methanolic extract of Premna integrifolia (MEPI) bark to investigate neuropharmacological, analgesic, and anti-inflammato...

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Bibliographic Details
Main Authors: Hajera Khatun, Rajib Majumder, Efte Kharul Alam, Al Mamun, Safkath Ibne Jami, Badrul Alam
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2014-05-01
Series:Avicenna Journal of Phytomedicine
Subjects:
Analgesic
antibacterial
CNS depressant
Inflammation
Premna integrifolia
Online Access:http://ajp.mums.ac.ir/pdf_2331_b44ebd8ce9eebc02d1facdb434b69847.html
Description
Summary:Objective: Premna integrifolia Linn (Family: Verbenaceae) synonym of Premna serratifolia has tremendous medicinal value. Preliminary pharmacological studies were performed on the methanolic extract of Premna integrifolia (MEPI) bark to investigate neuropharmacological, analgesic, and anti-inflammatory activities. Materials and methods: Neuropharmacology study was done by open field and hole cross test whereas acetic acid writhing test and formalin induced pain was done for analgesic activity of MEPI. Carrageenan induced inflammatory model was considered for anti-inflammatory activity evaluation.   Results: A statistically significant (p
ISSN:2228-7930
2228-7949

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