Diacetylenic lipids in the design of stable lipopolymers able to complex and protect plasmid DNA.

Different viral and non-viral vectors have been designed to allow the delivery of nucleic acids in gene therapy. In general, non-viral vectors have been associated with increased safety for in vivo use; however, issues regarding their efficacy, toxicity and stability continue to drive further resear...

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Bibliographic Details
Main Authors: C Facundo Temprana, M Jimena Prieto, Daniela E Igartúa, A Lis Femia, M Silvia Amor, Silvia Del Valle Alonso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5636127?pdf=render

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