Imputation for transcription factor binding predictions based on deep learning.

Understanding the cell-specific binding patterns of transcription factors (TFs) is fundamental to studying gene regulatory networks in biological systems, for which ChIP-seq not only provides valuable data but is also considered as the gold standard. Despite tremendous efforts from the scientific co...

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Bibliographic Details
Main Authors: Qian Qin, Jianxing Feng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5345877?pdf=render