A long lost key opens an ancient lock: Drosophila Myb causes a synthetic multivulval phenotype in nematodes

A long lost key opens an ancient lock: Drosophila Myb causes a synthetic multivulval phenotype in nematodes

The five-protein MuvB core complex is highly conserved in animals. This nuclear complex interacts with RB-family tumor suppressor proteins and E2F-DP transcription factors to form DREAM complexes that repress genes that regulate cell cycle progression and cell fate. The MuvB core complex also intera...

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Bibliographic Details
Main Authors: Paul J. Vorster, Paul Goetsch, Tilini U. Wijeratne, Keelan Z. Guiley, Laura Andrejka, Sarvind Tripathi, Braden J. Larson, Seth M. Rubin, Susan Strome, Joseph S. Lipsick
Format: Article
Language:English
Published: The Company of Biologists 2020-05-01
Series:Biology Open
Subjects:
myb
development
evolution
oncogene
synmuv
tumor suppressor
Online Access:http://bio.biologists.org/content/9/5/bio051508

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