Suppression of IRE1α Attenuated the Fatty Degeneration in Parenteral Nutrition-Related Liver Disease (PNALD) Cell Model

Suppression of IRE1α Attenuated the Fatty Degeneration in Parenteral Nutrition-Related Liver Disease (PNALD) Cell Model

Aims. To model the parenteral nutrition-associated liver disease (PNALD) in rat normal hepatocytes BRL and investigate the role of endoplasmic reticulum stress- (ERS-) related IRE1α signal in the process of PNALD. Methods. The BRL cells were treated with different concentrations of soybean oil emuls...

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Bibliographic Details
Main Authors: Ningxun Cui, Mingling Cui, Jie Li, Xueping Zhu, Xiaoli Zhu
Format: Article
Language:English
Published: Hindawi Limited 2020-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2020/7517540

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