WARFARIN INDUCED MASSIVE AND BILATERAL SKIN NECROSIS OF THE BREASTS: A CASE REPORT AND REVIEW OF THE LITERATURES
Warfarin induced skin necrosis is a rare complication associated with the use of oral anticoagulants. Most patients develop this complication at the initiation of therapy. The complication is usually associated with an underlying thrombophilia. Here we describe a case of a 75 year old patient who...
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2005-07-01
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| Series: | Acta Medica Iranica |
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| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/2069.pdf&manuscript_id=2069 |
| Summary: | Warfarin induced skin necrosis is a rare complication associated with the use of oral anticoagulants. Most patients develop this complication at the initiation of therapy. The complication is usually associated with an underlying thrombophilia. Here we describe a case of a 75 year old patient who developed skin necrosis in her both breasts during warfarin treatment for a deep vein thrombosis. Thrombophilia screening demonstrated the presence of protein S and antithrombin III deficiency. The necrotic lesion was excised and defects eventually covered with skin flaps. |
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| ISSN: | 0044-6025 |