Dynamical Models for Infectious Diseases with Varying Population Size and Vaccinations

• Main Authors: Peilin Shi, Lingzhen Dong
• Format: Article
• Language: English
• Published: Hindawi Limited 2012-01-01
• Series: Journal of Applied Mathematics
• Online Access: http://dx.doi.org/10.1155/2012/824192

We formulate and discuss models for the spread of infectious diseases with variable population sizes and vaccinations on the susceptible individuals. First, we assume that the susceptible individuals are vaccinated continuously. We establish the threshold-like results for the existence and global stability of the disease-free and the endemic equilibriums for these systems. Especially, we prove the global stability of the endemic equilibriums by converting the systems into integrodifferential equations. Second, we suppose that vaccinations occur once per time period. We obtain the existence and global stability of the disease-free periodic solutions for such systems with impulsive effects. By a useful bifurcation theorem, we acquire the existence of the endemic periodic solutions when the disease-related deaths do not occur. At last, we compare the results with vaccinations and without vaccinations and illustrate our results by numerical simulations.