Modulation the crosstalk between tumor-associated macrophages and non-small cell lung cancer to inhibit tumor migration and invasion by ginsenoside Rh2

Modulation the crosstalk between tumor-associated macrophages and non-small cell lung cancer to inhibit tumor migration and invasion by ginsenoside Rh2

Abstract Background Tumor-associated macrophages (TAMs) play a critical role in modulating the tumor microenvironment and promote tumor metastases. Our studies have demonstrated that ginsenoside Rh2 (G-Rh2), a monomeric compound extracted from ginseng, is a promising anti-tumor agent in lung cancer...

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Bibliographic Details
Main Authors: Honglin Li, Nan Huang, Weikang Zhu, Jianchun Wu, Xiaohui Yang, Wenjing Teng, Jianhui Tian, Zhihong Fang, Yingbin Luo, Min Chen, Yan Li
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Cancer
Subjects:
Ginsenoside Rh2 (G-Rh2)
Tumor-associated macrophage (TAM)
Vascular endothelial growth factor (VEGF)
Matrix metalloproteinases (MMPs)
Non-small cell lung cancer (NSCLC)
Online Access:http://link.springer.com/article/10.1186/s12885-018-4299-4

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http://link.springer.com/article/10.1186/s12885-018-4299-4

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