Novel combined variants of WT1 and TET2 in a refractory and recurrent AML patient

Abstract Background Somatic mutations in Wilms' tumor 1 (WT1) and tet methylcytosine dioxygenase 2 (TET2) genes were separately perceived as contributors to hematopoietic disorders and usually thought to have a mutually exclusive effect in acute myeloid leukemia (AML). However, we found novel W...

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Bibliographic Details
Main Authors: Qiang Ma, Yixian Guo, Xiaoxi Lan, Guoxiang Wang, Wanling Sun
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Medical Genomics
Subjects:
WT1
Online Access:https://doi.org/10.1186/s12920-021-01002-0