SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity
SARS-CoV-2 variants with spike (S)-protein D614G mutations currently predominate globally. Here, Zhang et al. hypothesize that D614G variant may increase infectivity by increasing S protein abundance on the virion since pseudoviruses carrying S-G614 incorporate higher amounts of S protein and enter...
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Bibliographic Details
| Main Authors: |
Lizhou Zhang,
Cody B. Jackson,
Huihui Mou,
Amrita Ojha,
Haiyong Peng,
Brian D. Quinlan,
Erumbi S. Rangarajan,
Andi Pan,
Abigail Vanderheiden,
Mehul S. Suthar,
Wenhui Li,
Tina Izard,
Christoph Rader,
Michael Farzan,
Hyeryun Choe |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2020-11-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-020-19808-4
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