GABAergic signaling is linked to a hypermigratory phenotype in dendritic cells infected by Toxoplasma gondii.

GABAergic signaling is linked to a hypermigratory phenotype in dendritic cells infected by Toxoplasma gondii.

During acute infection in human and animal hosts, the obligate intracellular protozoan Toxoplasma gondii infects a variety of cell types, including leukocytes. Poised to respond to invading pathogens, dendritic cells (DC) may also be exploited by T. gondii for spread in the infected host. Here, we r...

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Bibliographic Details
Main Authors: Jonas M Fuks, Romanico B G Arrighi, Jessica M Weidner, Suresh Kumar Mendu, Zhe Jin, Robert P A Wallin, Bence Rethi, Bryndis Birnir, Antonio Barragan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3516538?pdf=render

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