A simple method using ex vivo culture of hair follicle tissue to investigate intrinsic circadian characteristics in humans
Abstract Almost all organisms maintain a circadian clock from birth to death to synchronize their own physiology and behavior with the earth’s rotation. Because the in vivo evaluation of human circadian characteristics is labor-intensive, in vitro or ex vivo approaches could provide advantages. In t...
Main Authors: | Ai Yamaguchi, Ritsuko Matsumura, Takashi Matsuzaki, Wataru Nakamura, Koichi Node, Makoto Akashi |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-07268-8 |
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