A simple method using ex vivo culture of hair follicle tissue to investigate intrinsic circadian characteristics in humans

Abstract Almost all organisms maintain a circadian clock from birth to death to synchronize their own physiology and behavior with the earth’s rotation. Because the in vivo evaluation of human circadian characteristics is labor-intensive, in vitro or ex vivo approaches could provide advantages. In t...

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Bibliographic Details
Main Authors: Ai Yamaguchi, Ritsuko Matsumura, Takashi Matsuzaki, Wataru Nakamura, Koichi Node, Makoto Akashi
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07268-8