Efficacy of minute virus of mice (MVM) inactivation utilizing high temperature short time (HTST) pasteurization and suitability assessment of pasteurized, concentrated glucose feeds in Chinese hamster ovary (CHO) cell expression systems
Abstract There is a growing need to provide effective adventitious agent mitigation for high risk upstream cell culture raw materials used for the production of biologics. It is also highly important in the growing fields of cell and gene therapies. Glucose is a critical raw material necessary for e...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley-VCH
2021-07-01
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Series: | Engineering in Life Sciences |
Subjects: | |
Online Access: | https://doi.org/10.1002/elsc.202100044 |