The Cooperative Relationship between STAT5 and Reactive Oxygen Species in Leukemia: Mechanism and Therapeutic Potential

Reactive oxygen species (ROS) are now recognized as important second messengers with roles in many aspects of signaling during leukemogenesis. They serve as critical cell signaling molecules that regulate the activity of various enzymes including tyrosine phosphatases. ROS can induce inactivation of...

Full description

Bibliographic Details
Main Authors: Tian Mi, Zhengqi Wang, Kevin D. Bunting
Format: Article
Language:English
Published: MDPI AG 2018-09-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/10/10/359