Synthesis, Optimization, Characterization and Antimicrobial Studies of Cu(II) and Co(III) Complexes of Bis(2,2/-methylylidenephenol)diaminoethane
A new synthetic extractive protocol for the synthesis of Cu(II) and Co(III) complexes of bis(2,2/-methylylidenephenol)diaminoethane (H2BMPDE) in a single simple step was performed. The obtained data indicated the formation of complexes with 1:1 molar ratio of metal:ligand, of distorted square planar...
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Academy of Sciences of Moldova, Institute of Chemistry
2017-12-01
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| Series: | Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry |
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http://cjm.asm.md/sites/default/files/article_files/ChemJMold_10.19261cjm.2017.392-Nworie.pdf
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doaj-5a746c0cd4ee4ef1b8cf4d444aa2f7cf2021-07-02T02:18:33ZengAcademy of Sciences of Moldova, Institute of ChemistryChemistry Journal of Moldova: General, Industrial and Ecological Chemistry1857-17272345-16882017-12-01122414910.19261/cjm.2017.392392Synthesis, Optimization, Characterization and Antimicrobial Studies of Cu(II) and Co(III) Complexes of Bis(2,2/-methylylidenephenol)diaminoethaneFelix Sunday Nworie0Frank Ikenna Nwabue1 Department of Industrial Chemistry, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria Department of Industrial Chemistry, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria A new synthetic extractive protocol for the synthesis of Cu(II) and Co(III) complexes of bis(2,2/-methylylidenephenol)diaminoethane (H2BMPDE) in a single simple step was performed. The obtained data indicated the formation of complexes with 1:1 molar ratio of metal:ligand, of distorted square planar and distorted octahedral geometries. In vitro antibacterial screening revealed that the complexes were active against clinically important gram-negative bacteria (Escherichia coli, pseudomonas, and gram-positive bacterium (Staphylococcus aureus). The synthesis of the complexes was optimized to make it more suitable and efficient for industrial scale production. http://cjm.asm.md/sites/default/files/article_files/ChemJMold_10.19261cjm.2017.392-Nworie.pdf H2BMPDE-complexmodellingphysicochemical studyantimicrobial bio-efficiency |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Felix Sunday Nworie Frank Ikenna Nwabue |
| spellingShingle |
Felix Sunday Nworie Frank Ikenna Nwabue Synthesis, Optimization, Characterization and Antimicrobial Studies of Cu(II) and Co(III) Complexes of Bis(2,2/-methylylidenephenol)diaminoethane Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry H2BMPDE-complex modelling physicochemical study antimicrobial bio-efficiency |
| author_facet |
Felix Sunday Nworie Frank Ikenna Nwabue |
| author_sort |
Felix Sunday Nworie |
| title |
Synthesis, Optimization, Characterization and Antimicrobial Studies of Cu(II) and Co(III) Complexes of Bis(2,2/-methylylidenephenol)diaminoethane |
| title_short |
Synthesis, Optimization, Characterization and Antimicrobial Studies of Cu(II) and Co(III) Complexes of Bis(2,2/-methylylidenephenol)diaminoethane |
| title_full |
Synthesis, Optimization, Characterization and Antimicrobial Studies of Cu(II) and Co(III) Complexes of Bis(2,2/-methylylidenephenol)diaminoethane |
| title_fullStr |
Synthesis, Optimization, Characterization and Antimicrobial Studies of Cu(II) and Co(III) Complexes of Bis(2,2/-methylylidenephenol)diaminoethane |
| title_full_unstemmed |
Synthesis, Optimization, Characterization and Antimicrobial Studies of Cu(II) and Co(III) Complexes of Bis(2,2/-methylylidenephenol)diaminoethane |
| title_sort |
synthesis, optimization, characterization and antimicrobial studies of cu(ii) and co(iii) complexes of bis(2,2/-methylylidenephenol)diaminoethane |
| publisher |
Academy of Sciences of Moldova, Institute of Chemistry |
| series |
Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry |
| issn |
1857-1727 2345-1688 |
| publishDate |
2017-12-01 |
| description |
A new synthetic extractive protocol for the synthesis of Cu(II) and Co(III) complexes of bis(2,2/-methylylidenephenol)diaminoethane (H2BMPDE) in a single simple step was performed. The obtained data indicated the formation of complexes with 1:1 molar ratio of metal:ligand, of distorted square planar and distorted octahedral geometries. In vitro antibacterial screening revealed that the complexes were active against clinically important gram-negative bacteria (Escherichia coli, pseudomonas, and gram-positive bacterium (Staphylococcus aureus). The synthesis of the complexes was optimized to make it more suitable and efficient for industrial scale production. |
| topic |
H2BMPDE-complex modelling physicochemical study antimicrobial bio-efficiency |
| url |
http://cjm.asm.md/sites/default/files/article_files/ChemJMold_10.19261cjm.2017.392-Nworie.pdf
|
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