Exposure to Phthalates and Alternative Plasticizers Is Associated with Methylation Changes of ESR1 and PGR in Uterine Leiomyoma: The ELENA Study

Exposure to Phthalates and Alternative Plasticizers Is Associated with Methylation Changes of ESR1 and PGR in Uterine Leiomyoma: The ELENA Study

Uterine leiomyomas are estrogen-dependent benign tumors with unknown etiologies. Phthalates are endocrine-disrupting chemicals and ubiquitous in the environment; thus, it has been suggested that they play a role in the development of uterine leiomyoma. We aimed to investigate whether the pathogenesi...

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Bibliographic Details
Main Authors: Yoon Hee Cho, Yeong Sook Yoon, Min Sun Koo, Wanseo Kim, Younglim Kho, Sunmi Kim, Yang Jee Kim, Haewon Choi, Eun Jeong Choi, Jae Whoan Koh, Kyoung Chul Chun, Young Ah Kim
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Applied Sciences
Subjects:
leiomyoma
phthalates
alternative plasticizers
methylation
<i>ESR1</i>
<i>PGR</i>
Online Access:https://www.mdpi.com/2076-3417/11/9/4234

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https://www.mdpi.com/2076-3417/11/9/4234

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