IL-10 immunomodulation of myeloid cells regulates a murine model of ovarian cancer

IL-10 immunomodulation of myeloid cells regulates a murine model of ovarian cancer

AbstractElevated levels of IL-10 in the microenvironment of human ovarian cancer and murine models of ovarian cancer are well established and correlate with poor clinical prognosis. However, amongst a myriad of immunosuppressive factors, the actual contribution of IL-10 to the ovarian tumor microenv...

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Bibliographic Details
Main Authors: Kevin eHart, Katelyn eByrne, Michael eMolloy, Edward eUsherwood, Brent eBerwin
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-07-01
Series:Frontiers in Immunology
Subjects:
IL-10
T cell
ovarian cancer
MDSC
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00029/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2011.00029/full

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