Struma ovarii with follicular thyroid-type carcinoma and neuroendocrine component: case report

<p>Abstract</p> <p>Struma ovarii (SO) is a slow-growing ovarian neoplasm with thyroid tissue as its predominant component. It is an uncommon neoplasm, usually asymptomatic with an unknown risk of malignant transformation. Due to difficulties in assessing the rare biological nature...

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Bibliographic Details
Main Authors: Selvaggi Federico, Risio Domenico, Waku Mathew, Simo Daniela, Angelucci Domenico, D’Aulerio Alberto, Cotellese Roberto, Innocenti Paolo
Format: Article
Language:English
Published: BMC 2012-05-01
Series:World Journal of Surgical Oncology
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Online Access:http://www.wjso.com/content/10/1/93
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Summary:<p>Abstract</p> <p>Struma ovarii (SO) is a slow-growing ovarian neoplasm with thyroid tissue as its predominant component. It is an uncommon neoplasm, usually asymptomatic with an unknown risk of malignant transformation. Due to difficulties in assessing the rare biological nature and the discrepancies in the reported cases, a consensus on the appropriate treatment has not been definitively reached.</p> <p>A 50-year-old female was subjected to upper gut endoscopy which showed a 30-mm mass located in the gastric antrum, suggestive of mesenchimal tumor. Incidentally, a pelvic CT scan also documented a solid mass in the right adnexa, with morphological characteristics of ovarian neoplasm. The patient underwent gastrectomy, total hysterectomy, bilateral salpingo-oophorectomy with lymph node dissection, and omentectomy. Histology documented the presence of gastric cavernous angioma, and, in the right adnexa, foci of follicular thyroid-type carcinoma arising in SO with a well-differentiated neuroendocrine component.</p> <p>Here we report and discuss the clinical and morphological presentation of follicular thyroid-type carcinoma arising in SO. The neoplasm was discovered incidentally and had a favorable clinical outcome at 1-year follow-up.</p>
ISSN:1477-7819